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松果体胶质囊肿导致的猝死。

Sudden death due to a glial cyst of the pineal gland.

作者信息

Milroy C M, Smith C L

机构信息

Department of Forensic Pathology, University of Sheffield.

出版信息

J Clin Pathol. 1996 Mar;49(3):267-9. doi: 10.1136/jcp.49.3.267.

DOI:10.1136/jcp.49.3.267
PMID:8675746
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC500415/
Abstract

Asymptomatic cysts of the pineal gland are found frequently by radiological examination of the brain or at postmortem examination. Symptomatic cysts are rare, and may require surgical intervention. Sudden death due to a cystic lesion of the pineal gland is very rare. A case of a 22 year old man who collapsed and died unexpectedly is reported. Postmortem examination revealed a glial cyst of the pineal gland and evidence of chronic obstructive hydrocephalus. Deaths from colloid cysts and pineal gland cysts are rare, but should be considered where no other cause of death is evident, especially with a history of headaches. Their small size, and their possible rupture on dissection can make them difficult to detect if a careful examination is not undertaken.

摘要

松果体无症状囊肿在脑部放射学检查或尸检时经常被发现。有症状的囊肿很罕见,可能需要手术干预。因松果体囊性病变导致的猝死非常罕见。本文报告一例22岁男性意外倒地死亡的病例。尸检发现松果体有一个胶质囊肿以及慢性梗阻性脑积水的证据。胶体囊肿和松果体囊肿导致的死亡很罕见,但在没有其他明显死因,尤其是有头痛病史的情况下应予以考虑。它们体积小,解剖时可能破裂,如果不进行仔细检查,可能难以发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68a6/500415/d9af3710f831/jclinpath00240-0078-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68a6/500415/53051e0dd200/jclinpath00240-0078-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68a6/500415/d9af3710f831/jclinpath00240-0078-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68a6/500415/53051e0dd200/jclinpath00240-0078-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68a6/500415/d9af3710f831/jclinpath00240-0078-b.jpg

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Sudden death due to a glial cyst of the pineal gland.松果体胶质囊肿导致的猝死。
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2
Germline and somatic mutations in the pathology of pineal cyst: A whole-exome sequencing study of 93 individuals.松果体囊肿病理的胚系和体细胞突变:93 例个体的全外显子组测序研究。
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3
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本文引用的文献

1
Pineal cysts: an incidental MRI finding?松果体囊肿:MRI偶然发现?
J Neurol Neurosurg Psychiatry. 1993 Feb;56(2):207-8. doi: 10.1136/jnnp.56.2.207.
2
Incidental high-intensity foci in white matter on T2-weighted magnetic resonance imaging. Frequency and clinical significance in symptom-free adults.
Neuroradiology. 1993;35(2):151-5. doi: 10.1007/BF00593975.
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Sudden and unexpected death in childhood due to a colloid cyst of the third ventricle.
J Forensic Sci. 1993 Jan;38(1):210-3.
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人类松果体的年龄相关变化:一项针对尸检病例的数字解剖组织学形态计量学研究,并与数字时代之前的研究进行比较。
Medicina (Kaunas). 2021 Apr 15;57(4):383. doi: 10.3390/medicina57040383.
4
Pineal Cyst Apoplexy: A Rare Complication of Common Entity.松果体囊肿出血:一种常见疾病的罕见并发症。
Brain Tumor Res Treat. 2020 Apr;8(1):66-70. doi: 10.14791/btrt.2020.8.e4.
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Evaluation of pineal cysts with magnetic resonance imaging.磁共振成像对松果体囊肿的评估。
World J Radiol. 2018 Jul 28;10(7):65-77. doi: 10.4329/wjr.v10.i7.65.
6
Follow-up of pineal cysts in children: is it necessary?儿童松果体囊肿的随访:有必要吗?
Neuroradiology. 2017 Dec;59(12):1265-1273. doi: 10.1007/s00234-017-1926-8. Epub 2017 Sep 23.
7
Pineal cysts in children: case-based update.儿童松果体囊肿:基于病例的最新进展
Childs Nerv Syst. 2013 May;29(5):753-60. doi: 10.1007/s00381-012-2011-6. Epub 2013 Jan 3.
8
Visual evoked potentials in patients with pineal gland cyst.松果体囊肿患者的视觉诱发电位。
Wien Klin Wochenschr. 2012 Sep;124(17-18):605-10. doi: 10.1007/s00508-012-0215-0. Epub 2012 Aug 7.
9
High prevalence of pineal cysts in healthy adults demonstrated by high-resolution, noncontrast brain MR imaging.高分辨率非增强脑部磁共振成像显示健康成年人松果体囊肿的高患病率。
AJNR Am J Neuroradiol. 2007 Oct;28(9):1706-9. doi: 10.3174/ajnr.A0656. Epub 2007 Sep 20.
10
Pineal cysts in childhood.儿童松果体囊肿
Childs Nerv Syst. 2003 Nov;19(10-11):750-5. doi: 10.1007/s00381-003-0813-2. Epub 2003 Aug 14.
Symptomatic glial cysts of the pineal gland.松果体的症状性胶质囊肿。
J Neurosurg. 1994 Mar;80(3):454-60. doi: 10.3171/jns.1994.80.3.0454.
5
Sudden unexpected death caused by neuroepithelial (colloid) cyst of the third ventricle.
J Forensic Sci. 1981 Jul;26(3):486-91.
6
Sudden, unexpected death due to "pineal apoplexy".
Am J Forensic Med Pathol. 1986 Mar;7(1):64-8. doi: 10.1097/00000433-198603000-00014.
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Benign symptomatic glial cysts of the pineal gland: a report of seven cases and review of the literature.
J Neurol Neurosurg Psychiatry. 1989 Aug;52(8):991-5. doi: 10.1136/jnnp.52.8.991.