有证据表明，与单纯疱疹病毒1型DNA聚合酶相关的核酸酶活性是由3'-5'外切核酸酶引起的。
Evidence that the nuclease activities associated with the herpes simplex type 1 DNA polymerase are due to the 3'-5' exonuclease.
作者信息
Hall J D, Orth K L, Claus-Walker D
机构信息
Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721, USA.
出版信息
J Virol. 1996 Jul;70(7):4816-8. doi: 10.1128/JVI.70.7.4816-4818.1996.
Abstract
We investigated nuclease activities associated with the catalytic subunit of herpes simplex virus type 1 DNA polymerase. We confirm that a 3'-5' exonuclease copurifies with this enzyme. Previous reports suggested that a 5' DNase was intrinsic to the polymerase. Our preparation lacks such activity.
摘要
我们研究了与单纯疱疹病毒1型DNA聚合酶催化亚基相关的核酸酶活性。我们证实一种3'-5'核酸外切酶与该酶共纯化。先前的报道表明该聚合酶固有5'脱氧核糖核酸酶活性。而我们的制备物缺乏这种活性。
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本文引用的文献
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