从新几内亚分离出一种天然存在的重组爱泼斯坦-巴尔病毒，其编码1型和2型核抗原序列。
Identification of a naturally occurring recombinant Epstein-Barr virus isolate from New Guinea that encodes both type 1 and type 2 nuclear antigen sequences.
作者信息
Burrows J M, Khanna R, Sculley T B, Alpers M P, Moss D J, Burrows S R
机构信息
Epstein-Barr virus Unit, Queensland Institute of Medical Research, The Bancroft Centre, Brisbane, Australia.
出版信息
J Virol. 1996 Jul;70(7):4829-33. doi: 10.1128/JVI.70.7.4829-4833.1996.
Abstract
In this report we describe an Epstein-Barr virus isolate, derived from the peripheral blood lymphocytes of a healthy adult from Papua New Guinea, that is a recombinant of the two major Epstein-Barr virus types, encoding type 1 Epstein-Barr nuclear antigen 2 (EBNA2) sequences, and type 2 EBNA3, EBNA4, and EBNA6 sequences.
摘要
在本报告中，我们描述了一种源自巴布亚新几内亚一名健康成年人外周血淋巴细胞的爱泼斯坦-巴尔病毒分离株，它是两种主要爱泼斯坦-巴尔病毒类型的重组体，编码1型爱泼斯坦-巴尔核抗原2（EBNA2）序列以及2型EBNA3、EBNA4和EBNA6序列。
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本文引用的文献
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Unusually high frequency of Epstein-Barr virus genetic variants in Papua New Guinea that can escape cytotoxic T-cell recognition: implications for virus evolution.巴布亚新几内亚爱泼斯坦-巴尔病毒基因变体出现异常高频率，这些变体能够逃避细胞毒性T细胞识别：对病毒进化的影响
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Human oropharyngeal lesions with a defective Epstein-Barr virus that disrupts viral latency.具有缺陷型爱泼斯坦-巴尔病毒的人类口咽病变，该病毒破坏病毒潜伏状态。
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Heterogeneity within the Epstein-Barr virus nuclear antigen 2 gene in different strains of Epstein-Barr virus.不同株爱泼斯坦-巴尔病毒中爱泼斯坦-巴尔病毒核抗原2基因的异质性。
J Gen Virol. 1994 Jan;75 ( Pt 1):95-100. doi: 10.1099/0022-1317-75-1-95.
5
Detection of multiple 'Ebnotypes' in individual Epstein-Barr virus carriers following lymphocyte transformation by virus derived from peripheral blood and oropharynx.通过来自外周血和口咽的病毒进行淋巴细胞转化后，在个体爱泼斯坦-巴尔病毒携带者中检测多种“Ebnotypes” 。
J Gen Virol. 1994 Jan;75 ( Pt 1):85-94. doi: 10.1099/0022-1317-75-1-85.
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The Epstein-Barr virus EBNA-2 gene in oral hairy leukoplakia: strain variation, genetic recombination, and transcriptional expression.口腔毛状白斑中爱泼斯坦-巴尔病毒EBNA-2基因：毒株变异、基因重组及转录表达
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