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[高强度光对抑郁症患者儿茶酚胺排泄的作用]

[The action of high-intensity light on catecholamine excretion in depressive patients].

作者信息

Bozhko G Kh, Tsaritsinskiĭ V I, Strelianaia E I, Taranskaia A D

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 1996;96(1):58-60.

PMID:8677722
Abstract

The action of bright light (2600-2800 lux) on the catecholamine (CA) excretion was analyzed in patients with anxious (11) and melancholic (12) depressions resultant from manic-depressive psychosis and schizophrenia. The melancholic depressed patients were characterized by decreased noradrenaline (NA) and increased adrenaline (A) levels; in anxious depression NA and A were increased. The light therapy resulted in decrease of A level but NA level remained invariable in melancholic depression. Meanwhile the tendency to normalization of excretion of both CA was observed in anxious patients after light therapy. The contrary alterations in A/NA ratio as well as its considerable individual fluctuations were observed after light therapy. The A/NA ratio after light therapy depended mainly upon the initial A/NA ratio (the higher or lower ratio compared to control value).

摘要

对患有躁郁症和精神分裂症所致焦虑性抑郁(11例)和忧郁性抑郁(12例)的患者,分析了强光(2600 - 2800勒克斯)对儿茶酚胺(CA)排泄的作用。忧郁性抑郁患者的特点是去甲肾上腺素(NA)水平降低、肾上腺素(A)水平升高;而焦虑性抑郁患者的NA和A水平升高。光照疗法使忧郁性抑郁患者的A水平降低,但NA水平保持不变。同时,焦虑患者在光照疗法后观察到两种CA排泄有趋于正常化的趋势。光照疗法后观察到A/NA比值的相反变化及其相当大的个体波动。光照疗法后的A/NA比值主要取决于初始A/NA比值(与对照值相比更高或更低的比值)。

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