Sugano S, Suzuki T, Makino H, Yanagimoto S, Nishio M, Onmura H, Iinuma M, Matuda T, Shinozawa Y
Department of Internal Medicine, Gastroenterology/Hepatology Division, Saiseikai Wakakusa Hospital, Yokohama, Japan.
Am J Gastroenterol. 1996 Apr;91(4):777-9.
The protein C anticoagulant pathway is an important downregulating mechanism of the blood coagulation cascade. We report a 47-yr-old male with Budd-Chiari syndrome and occlusion of the inferior vena cava. His plasma protein C antigen level was decreased to 42%, and its activity was 34%. Other coagulable factors were normal. Protein C deficiency should be considered a possible etiological factor of the Budd-Chiari syndrome.