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胃复安和异丙嗪不会降低丙泊酚的催眠需求。

Metoclopramide and prochlorperazine do not decrease propofol hypnotic requirements.

作者信息

Ali P B, Graham S G

机构信息

University Department of Anaesthesia, Royal Victoria Infirmary.

出版信息

Anaesthesia. 1995 Nov;50(11):990-1. doi: 10.1111/j.1365-2044.1995.tb05937.x.

DOI:10.1111/j.1365-2044.1995.tb05937.x
PMID:8678261
Abstract

One hundred patients scheduled for minor surgery were given either saline, metoclopramide 0.1 mg.kg-1 or 0.2 mg.kg-1, or prochlorperazine 0.1 mg.kg-1 or 0.2 mg.kg-1 before induction of anaesthesia with a fixed rate infusion of propofol. Neither metoclopramide nor prochlorperazine reduced the induction dose of propofol. The possibility that these agents increased the induction dose could not be excluded.

摘要

一百名计划接受小手术的患者在以固定速率输注丙泊酚进行麻醉诱导前，分别给予生理盐水、0.1毫克/千克或0.2毫克/千克的甲氧氯普胺、或0.1毫克/千克或0.2毫克/千克的氯丙嗪。甲氧氯普胺和氯丙嗪均未降低丙泊酚的诱导剂量。也不能排除这些药物增加诱导剂量的可能性。

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