Kawaguchi M, Saito T, Ohno H, Midorikawa S, Sanji T, Handa Y, Morita S, Yoshida H, Tsurui M, Misaka R, Hirota T, Saito M, Minami K
Fourth Department of Internal Medicine, Tokyo Medical College, Japan.
J Gastroenterol. 1996 Apr;31(2):294-8. doi: 10.1007/BF02389534.
A microorganism with close immunohistological and genetic resemblance to Helicobacter pylori was found in the resected gallbladder mucosa of a 41-year-old woman. The woman was admitted to hospital complaining of fever and right hypochondrial pain. Cholecystectomy was carried out under the diagnosis of gallstones and cholecystitis. A microorganism resembling H. pylori (stained with H&E, Giemsa, and Wartin-Starry) was detected incidentally on pathological examination. The microorganism was also positive for immunohistochemical staining. An amplification reaction was seen on genetic examination by the polymerase chain reaction (PCR) method (urease beta-genes). Our findings suggest that H. pylori may be present in tissues other than gastric mucosa.
在一名41岁女性切除的胆囊黏膜中发现了一种在免疫组织学和基因方面与幽门螺杆菌极为相似的微生物。该女性因发热和右季肋部疼痛入院。在胆结石和胆囊炎的诊断下进行了胆囊切除术。病理检查时偶然发现一种类似幽门螺杆菌的微生物（经苏木精-伊红染色、吉姆萨染色和沃辛-斯塔里染色）。该微生物免疫组化染色也呈阳性。通过聚合酶链反应（PCR）方法（脲酶β基因）进行基因检测时出现了扩增反应。我们的研究结果表明，幽门螺杆菌可能存在于胃黏膜以外的组织中。
