Peeters P, Mets T
Department of Internal Medicine, Academic Hospital, Free University Brussels (VUB), Belgium.
J Gerontol A Biol Sci Med Sci. 1996 Jul;51(4):M147-51. doi: 10.1093/gerona/51a.4.m147.
The value of the 6-minute walk in a population of elderly patients with chronic heart failure (CHF) has not yet been established, as it has been in a younger population.
In a prospective trial, 2 exercise tests were compared: the 6-minute walk (6 MW) and a treadmill test with progressive increments in workload. 37 patients (mean age 81.3, SD 5.6 years): 11 untrained controls, 16 patients with New York Heart Association (NYHA) class II and 10 patients with NYHA class III participated. The main outcome measures were the distance walked in 6 minutes, the symptomatic VO2max in the progressive treadmill test and the degree of CHF as scored by the NYHA classification and the Boston Study Group (BSG) score.
For both the 6 MW and the treadmill test there was a significant difference in distance between NYHA class II and III patients (p < .001), between the controls and NYHA class III patients (p < .001), but not between the controls and NYHA class II patients. The distance walked in the 6 MW was well correlated with the distance walked in the treadmill test (p < .001). Eight participants (22%), however, were unable to perform this treadmill test and 6 participants (17%) covered very low distances compared to the 6 MW. The VO2max was lower in NYHA class III than in class II patients (p = .032). NYHA classification and BSG score correlated reasonably well.
A treadmill exercise test with VO2max measurement in elderly patients with CHF is difficult to accomplish. On the contrary, the 6 MW gives a good impression of the remaining exercise capacity. It is well correlated with the treadmill test. The 6 MW is well tolerated by elderly patients and differentiates between NYHA classes II and III. Untrained controls could not be differentiated from NYHA class II patients.
6分钟步行试验在老年慢性心力衰竭(CHF)患者群体中的价值尚未确定,而在年轻人群体中已得到确认。
在一项前瞻性试验中,对2种运动测试进行了比较:6分钟步行试验(6MW)和工作量逐步增加的跑步机测试。37名患者(平均年龄81.3岁,标准差5.6岁)参与其中,包括11名未经训练的对照组患者、16名纽约心脏协会(NYHA)II级患者和10名NYHA III级患者。主要结局指标为6分钟内行走的距离、递增式跑步机测试中的症状性最大摄氧量(VO2max)以及NYHA分级和波士顿研究组(BSG)评分所评估的CHF程度。
对于6MW和跑步机测试,NYHA II级和III级患者之间的行走距离存在显著差异(p < 0.001),对照组与NYHA III级患者之间也存在显著差异(p < 0.001),但对照组与NYHA II级患者之间无显著差异。6MW中行走的距离与跑步机测试中行走的距离高度相关(p < 0.001)。然而,8名参与者(22%)无法完成该跑步机测试,6名参与者(17%)与6MW相比行走距离非常短。NYHA III级患者的VO2max低于II级患者(p = 0.032)。NYHA分级与BSG评分相关性较好。
在老年CHF患者中进行带有VO2max测量的跑步机运动测试很难实现。相反,6MW能很好地反映剩余运动能力。它与跑步机测试相关性良好。老年患者对6MW耐受性良好,且能区分NYHA II级和III级患者。未经训练的对照组与NYHA II级患者无法区分。