[职业性和非职业性接触亚乙基双二硫代氨基甲酸盐的受试者中乙撑硫脲尿排泄的评估]
[Evaluation of urinary excretion of ethylenethiourea in subjects occupationally and non-occupationally exposed to ethylenebis(dithiocarbamates)].
作者信息
Sciarra G, Aprea C, Sartorelli P
机构信息
Istituto di Medicina del Lavoro, Università degli Studi di Siena.
出版信息
G Ital Med Lav. 1994 Jan-Nov;16(1-6):49-52.
Ethylenebisdithiorcabamate (EBDC) fungicides are broken down metabolically and in the environment to ethylenethiourea (ETU), a suspected carcinogen. Urinary ETU was assayed in control groups and subjects occupationaly exposed to EBDC and was found to be an excellent indicator of exposure both to ETU and EBDC. Correct use of protective clothing greatly reduced exposure and urinary excretion of ETU. ETU was excreted, albeit in low concentrations, in a high percentage (91% and 30%) of subjects in both control groups, demonstrating its utility as an indicator of widespread EBDC contamination.
亚乙基双二硫代氨基甲酸盐（EBDC）类杀菌剂在代谢过程中以及在环境中会分解为乙烯硫脲（ETU），一种疑似致癌物。对对照组和职业接触EBDC的受试者检测了尿中ETU，发现它是接触ETU和EBDC的良好指标。正确使用防护服可大大减少ETU的接触和尿排泄。在两个对照组中，高比例（91%和30%）的受试者都有ETU排泄，尽管浓度较低，这表明它可用作EBDC广泛污染的指标。
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