Raso D S, Greene W B, Harley R A, Maize J C
Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston 29425, USA.
J Am Acad Dermatol. 1996 Jul;35(1):32-6. doi: 10.1016/S0190-9622(96)90492-2.
The possible association of silicone breast implants and disease is a subject of continuous debate and concern.
Our purpose was to examine microscopically and ultrastructurally the periprosthetic fibrous capsules and reconstruction scars of women with silicone breast implants.
Representative samples from the periprosthetic capsules and reconstruction scars from six women with silicone breast implants were examined by a variety of light microscopy techniques, transmission electron microscopy, and electron probe microanalysis.
Silicone globules of various sizes were identified in every periprosthetic capsule and reconstruction scar.
Extrusion and seeding of the incision tract during surgery most likely accounts for the presence of silicone in the reconstruction scar specimens. This observation suggests that the identification of silicone in the reconstruction scars of women with silicone breast implants does not necessarily implicate rupture of the silicone breast implant with systemic dissemination of silicone gel.
硅胶乳房植入物与疾病之间可能存在的关联是一个持续争论和关注的话题。
我们的目的是对硅胶乳房植入物女性的假体周围纤维囊和重建瘢痕进行微观和超微结构检查。
通过多种光学显微镜技术、透射电子显微镜和电子探针微分析，对6例硅胶乳房植入物女性的假体周围囊和重建瘢痕的代表性样本进行检查。
在每个假体周围囊和重建瘢痕中均发现了各种大小的硅胶球。
手术过程中切口通道的挤压和播散很可能是重建瘢痕标本中存在硅胶的原因。这一观察结果表明，在硅胶乳房植入物女性的重建瘢痕中发现硅胶并不一定意味着硅胶乳房植入物破裂且硅胶凝胶发生全身播散。
