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红皮病。102例患者的临床及随访研究,特别关注生存率。

Erythroderma. A clinical and follow-up study of 102 patients, with special emphasis on survival.

作者信息

Sigurdsson V, Toonstra J, Hezemans-Boer M, van Vloten W A

机构信息

Department of Dermatology, University Hospital, Utrecht, The Netherlands.

出版信息

J Am Acad Dermatol. 1996 Jul;35(1):53-7. doi: 10.1016/s0190-9622(96)90496-x.

Abstract

BACKGROUND

Erythroderma may result from different causes. There have been no publications on this subject with special emphasis on survival.

OBJECTIVE

The aim of the study was to determine the cause of the erythroderma and the prognosis of these patients.

METHODS

Clinical and follow-up data from 102 patients with erythroderma were analyzed. We estimated survival of patients with erythroderma, from causes other than Sézary syndrome, mycosis fungoides, or leukemia cutis. The survival was compared with that of an age-matched control group of the general population.

RESULTS

The main cause of erythroderma was exacerbation of a preexisting dermatosis (53%). Drug reactions were rarely the cause (5%). A high proportion of the patients had chronic actinic dermatitis/actinic reticuloid (12%). Survival of men with erythroderma was significantly lower than that of the general population.

CONCLUSION

Men with erythroderma, from causes other than Sézary syndrome, mycosis fungoides, or leukemia cutis, have a lower survival than men in the general population.

摘要

背景

红皮病可能由不同原因引起。关于这个主题,尚未有特别强调生存率的相关出版物。

目的

本研究的目的是确定红皮病的病因以及这些患者的预后。

方法

分析了102例红皮病患者的临床和随访数据。我们评估了除 Sézary 综合征、蕈样肉芽肿或皮肤白血病之外的其他原因导致的红皮病患者的生存率。并将该生存率与年龄匹配的普通人群对照组进行比较。

结果

红皮病的主要病因是既往皮肤病加重(53%)。药物反应很少是病因(5%)。相当一部分患者患有慢性光化性皮炎/光化性类网状细胞增生症(12%)。红皮病男性患者的生存率显著低于普通人群。

结论

除 Sézary 综合征、蕈样肉芽肿或皮肤白血病之外的其他原因导致的红皮病男性患者,其生存率低于普通人群中的男性。

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