Mende H E, Reuter W, Koch G
Zentralbl Gynakol. 1977;99(6):330-6.
Complexometric determinations of serum magnesium levels, moreover partly of Mg concentrations in whole blood, and withal determinations of hematocrit in 489 healthy pregnancies, parturients, puerperants (1 to 10 days post partum), and nonpregnant women were performed. By aid of these values we were able to calculate Mg concentrations in 100 ml erythrocytes (Mg E 100). The apparent decrease of serum Mg during pregnancy may be founded according to the changes of the plasma volume. However, actually the total (absolute) ammount of serum Mg is increased in pregnancy. We suppose some influences on serum Mg due to stimulation of the thyroid gland in pregnancy and further those of Mg being released from the muscular cells of uterus those been destroyed after delivery. The increased erythrocyte Mg during pregnancy and post partum confirm the view that there are no corresponding relations between Mg concentrations of serum and those of erythrocytes. The possible causes of the increase of erythrocyte Mg in pregnancy are discussed in detail.
此外,还对489例健康孕妇、产妇、产后1至10天的产褥期妇女及非孕妇女进行了血清镁水平的络合滴定测定,部分测定了全血中的镁浓度,并测定了血细胞比容。借助这些数值,我们能够计算出每100毫升红细胞中的镁浓度(Mg E 100)。孕期血清镁的明显降低可能是根据血浆量的变化得出的。然而,实际上孕期血清镁的总量(绝对值)是增加的。我们推测孕期甲状腺受到刺激以及产后子宫肌细胞被破坏后释放出镁,这对血清镁有一定影响。孕期及产后红细胞镁含量的增加证实了血清镁浓度与红细胞镁浓度之间不存在相应关系这一观点。文中详细讨论了孕期红细胞镁含量增加的可能原因。