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[胃食管反流——手术指征、腹腔镜手术技术、结果]

[Gastroesophageal reflux--surgical indications, laparoscopic surgical technique, results].

作者信息

Dreuw B, Tittel A, Schippers E, Schumpelick V

机构信息

Chirurgische Klinik, der Medizinischen Fakultät, Rheinisch-Westfälische Technische Hochschule (RWTH), Aachen.

出版信息

Leber Magen Darm. 1996 Mar;26(2):88-94, 97.

PMID:8684249
Abstract

OBJECTIVE

To investigate criteria for indication to surgery and results of laparoscopic fundoplication.

BACKGROUND

Gastroesophageal reflux is a common problem in well developed countries. Beside clinical symptoms of heartburn and regurgitation complications may occur like esophagitis, bleeding, ulceration, mucosal metaplasia and loss of motility. A connection of reflux disease, Barrett's esophagus and adenocarcinoma of motility. A connection of reflux disease, Barrett's esophagus and adenocarcinoma of the esophagogastric junction is discussed. In some patients medical treatment is complicated by relapse, persistent or progressive disease. For these patients laparoscopic antireflux surgery may be an effective alternative.

PATIENTS

22 patients with chronic gastroesophageal reflux disease.

METHODS

Since 9-2-1922 patients with gastroesophageal reflux disease were prospectively evaluated and treated by laparoscopic Nissen fundoplication.

RESULTS

11 patients had frequent recurrent disease, 9 persistent reflux and 2 a stricture while on medical treatment. All had pathologic reflux on 24 hour pH monitoring and defective sphincter on standard manometry. Beside an intraoperative pneumothorax there was no intraoperative complication. Postoperative 2 patients had a temporary and 1 mild persisted dysphagia. None had recurrent reflux. 10 patients were reevaluated one year after surgery. None had an esophagitis, abnormal reflux or an insufficient or hypercontinent sphincter.

CONCLUSIONS

Patients with recurrent or persistent reflux while on medical treatment with abnormal reflux on pH monitoring and defective sphincter on manometry can be treated by laparoscopic Nissen fundoplication with good results.

摘要

目的

探讨手术指征标准及腹腔镜胃底折叠术的效果。

背景

胃食管反流在发达国家是一个常见问题。除了烧心和反流的临床症状外,还可能发生食管炎、出血、溃疡、黏膜化生和动力丧失等并发症。反流性疾病、巴雷特食管与食管胃交界腺癌之间的关联也在讨论中。在一些患者中,药物治疗会因病情复发、持续或进展而变得复杂。对于这些患者,腹腔镜抗反流手术可能是一种有效的替代方法。

患者

22例慢性胃食管反流病患者。

方法

自1992年2月起,对胃食管反流病患者进行前瞻性评估,并采用腹腔镜尼森胃底折叠术进行治疗。

结果

11例患者病情频繁复发,9例持续反流,2例在接受药物治疗时有狭窄。所有患者24小时pH监测均有病理性反流,标准测压显示括约肌功能不全。除术中气胸外,无术中并发症。术后2例患者有短暂性吞咽困难,1例有轻度持续性吞咽困难。无复发性反流。10例患者术后1年接受复查。均无食管炎、异常反流或括约肌功能不全或过强。

结论

在药物治疗期间复发或持续反流、pH监测显示异常反流且测压显示括约肌功能不全的患者,可通过腹腔镜尼森胃底折叠术进行治疗,效果良好。

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