Baldt M M, Zontsich T, Stümpflen A, Fleischmann D, Schneider B, Minar E, Mostbeck G H
Department of Radiology, University of Vienna Medical School, Austria.
Radiology. 1996 Aug;200(2):423-8. doi: 10.1148/radiology.200.2.8685336.
To compare the efficacy of spiral computed tomographic (CT) venography with conventional venography in the diagnosis of suspected deep venous thrombosis (DVT).
In a prospective study, 52 consecutive patients with clinically suspected unilateral or bilateral DVT were studied with CT venography and conventional venography. In cases in which conventional venographic findings were inconclusive, color-coded duplex sonography and follow-up examinations were performed to make a final diagnosis. CT venography of both extremities covered a 100-cm section from the ankle to the inferior vena cava (IVC). Contrast material diluted with saline was injected in a dorsal vein of each foot. CT and conventional venography (including color-coded duplex sonography and follow-up findings) were correlated for three venous regions for each patient.
Correlation was excellent between CT and conventional venographic findings in the detection of DVT. The sensitivity of CT venography was 100% (confidence interval: 0.92, 1.00), specificity was 96% (confidence interval: 0.84, 0.98), positive predictive value was 91%, and negative predictive value was 100%. CT venography more clearly demonstrated thrombus extension of DVT into the pelvic veins and IVC than conventional venography alone.
CT venography is a valuable tool in the diagnosis of DVT. Compared with conventional venography, CT requires use of 80% less contrast material.
比较螺旋计算机断层扫描（CT）静脉造影与传统静脉造影在诊断疑似深静脉血栓形成（DVT）中的疗效。
在一项前瞻性研究中，对52例临床疑似单侧或双侧DVT的连续患者进行了CT静脉造影和传统静脉造影检查。对于传统静脉造影结果不明确的病例，进行了彩色编码双功超声检查和随访检查以做出最终诊断。双下肢CT静脉造影覆盖从踝关节至下腔静脉（IVC）的100 cm段。将用生理盐水稀释的造影剂注入每只脚的背静脉。对每位患者的三个静脉区域的CT和传统静脉造影（包括彩色编码双功超声检查和随访结果）进行相关性分析。
在DVT检测中，CT与传统静脉造影结果之间的相关性极佳。CT静脉造影的敏感性为100%（置信区间：0.92，1.00），特异性为96%（置信区间：0.84，0.98），阳性预测值为91%，阴性预测值为100%。与单独的传统静脉造影相比，CT静脉造影更清楚地显示了DVT血栓延伸至盆腔静脉和IVC。
CT静脉造影是诊断DVT的一种有价值的工具。与传统静脉造影相比，CT所需的造影剂用量减少80%。
