Schweizer J, Mück-Weymann M, Klemm E
Abteilung für Angiologie, Medizinischen Klinik des Städtischen Klinikums Dresden-Friedrichstadt.
Ultraschall Med. 1996 Apr;17(2):68-71. doi: 10.1055/s-2007-1003149.
The aim of the present study was to clarify, by means of transcranial colour-coded duplex sonography of the basilar artery, whether there are changes in basilar artery blood flow in patients with acute inner ear disturbances and whether the flow in the basilar artery is affected by acoustic stimuli in such patients and in normal, healthy controls.
Basilar artery blood flow velocity was measured in 52 patients with severe inner ear impairment over a period of two weeks by means of conventional transcranial Doppler sonography and transcranial colour-coded duplex sonography. The same measurements were carried out in 45 healthy control subjects. At the end of the two week period, both patients and controls were exposed to 70-dB noise, with basilar artery flow evaluated before and during exposure. The basilar artery Doppler curves were analysed for systolic flow velocity, end-diastolic flow velocity, resistance index (Pourcelot) and pulsatility index (Gosling).
During the first two days of the study, the basilar artery resistance index and pulsatility index were significantly (p < 0.001) higher in patients than in controls. During noise exposure, both patients and controls showed significant (p < 0.01) increases in these indices.
This study shows that temporary increases in the basilar artery resistance index and pulsatility index are found both in the acute phase of inner ear disease and during exposure to noise.
本研究旨在通过对基底动脉进行经颅彩色编码双功超声检查,明确急性内耳功能障碍患者的基底动脉血流是否存在变化,以及此类患者和正常健康对照者的基底动脉血流是否受声刺激影响。
采用传统经颅多普勒超声和经颅彩色编码双功超声,对52例严重内耳功能损害患者的基底动脉血流速度进行了为期两周的测量。45名健康对照者也进行了同样的测量。在两周期末,患者和对照者均暴露于70分贝的噪声中,在暴露前和暴露期间评估基底动脉血流。分析基底动脉多普勒曲线的收缩期血流速度、舒张末期血流速度、阻力指数(普塞尔洛指数)和搏动指数(戈斯林指数)。
在研究的前两天,患者的基底动脉阻力指数和搏动指数显著高于对照者(p < 0.001)。在噪声暴露期间,患者和对照者的这些指数均显著升高(p < 0.01)。
本研究表明,在内耳疾病急性期和噪声暴露期间,基底动脉阻力指数和搏动指数均会出现暂时升高。