Evstropov A N, Iavorovskaia V E, Galegov G A
Vopr Virusol. 1996 Mar-Apr;41(2):66-70.
The therapeutic effect of nonsteroid antiinflammatory drugs (pyrazolone and salicylate derivatives) and their combinations with acyclovir was assessed in experimental herpesvirus infection in cell culture and in mice. A combination of 4-iodoantipyrine and acyclovir protected mice from herpesvirus encephalitis. This effect was associated with a decrease of the level of the virus in mouse brain and an increase of the titers of serum interferon and virus neutralizing antibodies.
在细胞培养和小鼠的实验性疱疹病毒感染中，评估了非甾体抗炎药（吡唑啉酮和水杨酸盐衍生物）及其与阿昔洛韦联合使用的治疗效果。4-碘安替比林与阿昔洛韦的组合可保护小鼠免受疱疹病毒性脑炎的侵害。这种效果与小鼠脑中病毒水平的降低以及血清干扰素和病毒中和抗体滴度的增加有关。
