Nasr F, Becam A M, Herbert C J
Centre de Génétique Moléculaire, Laboratoire propre du CNRS associé à l'Université Pierre et Marie Curie, Gif-sur-Yvette, France.
Yeast. 1996 Feb;12(2):169-75. doi: 10.1002/(sici)1097-0061(199602)12:2<169::aid-yea894>3.0.co;2-b.
We have determined the complete nucleotide sequence of a 36.8 kb segment from the left arm of chromosome XIV carried by the cosmid 14-11. The sequence encodes the 5' coding region of the PSD1 gene, the 3' coding region of an unknown gene and 24 complete open reading frames, of which 18 correspond to new genes and six (SKO1, SCL41A, YGP1, YCK2, RPC31 and MFA2) have been sequenced previously. Of the 24 new genes, five show significant similarities to sequences present in the databanks. These include elongation factors 2 and the human myotonic dystrophy kinase.
我们已经确定了黏粒14 - 11所携带的来自第十四号染色体左臂的一段36.8 kb片段的完整核苷酸序列。该序列编码PSD1基因的5'编码区、一个未知基因的3'编码区以及24个完整的开放阅读框,其中18个对应新基因,6个(SKO1、SCL41A、YGP1、YCK2、RPC31和MFA2)先前已被测序。在这24个新基因中,有5个与数据库中的序列有显著相似性。这些包括延伸因子2和人类强直性肌营养不良激酶。