Tone O, Ito U, Tomita H, Akimoto H, Sakemi H
Department of Neurosurgery, Musashino Red Cross Hospital, Tokyo Japan.
Acta Neurol Scand Suppl. 1996;166:18-21. doi: 10.1111/j.1600-0404.1996.tb00535.x.
The means of the cerebral blood flow (CBF) values obtained by the stable xenon enhanced CT (Xe/CT) method using two different CT scanners were compared with global CBF value obtained by the Kety-Schmidt (N2O) method as a reference. Xe/CT CBF values were obtained using a GE CT9200 (31 patients, 2 flow maps, 120 kV, absorption constant of 0.040) as well as a GE ProSeed Accell (38 patients, 4 flow maps, 80 kV, absorption constant of 0.028). The protocol of inhalation in the Xe/XT method consisted of 4 min wash-in and 4-min wash-out of 35% stable xenon. In the Kety-Schmidt method, 15% N2O gas was inhaled for 10 min. The N2O content of blood samples was measured using a van Slyke-Neill blood gas analyzer. We corrected all obtained CBF values for a PaCO2 of 34 mmHG (CBF34). The global CBF34 values obtained by the Kety-Schmidt method were linearly correlated with the CBF34 values obtained using the CT9200 and with those obtained using the ProSeed Accell, and the regression line equations were, respectively, Y = 0.64X + 13.7 (X: CT9200, Y: Kety-Schmidt, r = 0.666, p < 0.01) and Y = 0.99X + 11.2 (X: ProSeed Accell, Y: Kety Schmidt, r = 0.756, p < 0.01). Since the CBF values obtained by the Xe/CT method using different CT scanners are not always the same as the global CBF values obtained by the Kety-Schmidt method, CBF values obtained by the Xe/CT method should be corrected referring to the regression line obtained by applying both methods for each patient.
将使用两种不同CT扫描仪的稳定氙增强CT（Xe/CT）方法获得的脑血流量（CBF）值的均值，与作为参考的通过Kety-Schmidt（N2O）方法获得的全脑CBF值进行比较。使用GE CT9200（31例患者，2张血流图，120 kV，吸收常数0.040）以及GE ProSeed Accell（38例患者，4张血流图，80 kV，吸收常数0.028）获得Xe/CT CBF值。Xe/XT方法中的吸入方案包括35%稳定氙的4分钟洗入和4分钟洗出。在Kety-Schmidt方法中，吸入15% N2O气体10分钟。使用范斯莱克-尼尔血气分析仪测量血样中的N2O含量。我们将所有获得的CBF值校正为PaCO2为34 mmHg时的值（CBF34）。通过Kety-Schmidt方法获得的全脑CBF34值与使用CT9200获得的CBF34值以及使用ProSeed Accell获得的CBF34值呈线性相关，回归线方程分别为Y = 0.64X + 13.7（X：CT9200，Y：Kety-Schmidt，r = 0.666，p < 0.01）和Y = 0.99X + 11.2（X：ProSeed Accell，Y：Kety Schmidt，r = 0.756，p < 0.01）。由于使用不同CT扫描仪的Xe/CT方法获得的CBF值并不总是与Kety-Schmidt方法获得的全脑CBF值相同，因此对于通过Xe/CT方法获得的CBF值，应参考针对每位患者应用两种方法所获得的回归线进行校正。
