Lyons B, Frizelle H, Kirby F, Casey W
Department of Anaesthesia, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland.
Anaesthesia. 1996 Apr;51(4):324-6. doi: 10.1111/j.1365-2044.1996.tb07740.x.
The aim of this study was to assess whether passive smoking affected the frequency of airway complications in children undergoing general anaesthesia. One hundred and twenty-five children undergoing general anaesthesia for elective daycase surgery were monitored for adverse respiratory events and desaturation during induction, intra-operatively and in the recovery room. Oxygen saturation was monitored throughout and a venous sample was taken for estimation of carboxyhaemoglobin levels. Parents were asked to fill in a questionnaire detailing their smoking habits. Sixty-three of the children were passive smokers with a potential daily exposure varying from 5-130 cigarettes. There was no difference in the frequency of respiratory events between passive smokers and those not exposed to cigarette smoke at induction or intra-operatively. However, in the recovery room, desaturation was significantly more common in passive smokers (p < 0.02). This was related to the cumulative number of cigarettes smoked by individuals to whom the child was exposed (p < 0.05). Neither carboxyhaemoglobin levels nor domiciliary address were predictive of desaturation. This study suggests that passive smoking contributes to postoperative arterial oxygen desaturation following general anaesthesia in children.
本研究的目的是评估被动吸烟是否会影响接受全身麻醉的儿童气道并发症的发生率。对125名接受择期日间手术全身麻醉的儿童在诱导期、术中及恢复室进行了不良呼吸事件和血氧饱和度下降的监测。全程监测血氧饱和度，并采集静脉血样以测定碳氧血红蛋白水平。要求家长填写一份详细说明其吸烟习惯的问卷。其中63名儿童是被动吸烟者，其潜在的每日接触量为5 - 130支香烟。被动吸烟者与未接触香烟烟雾者在诱导期或术中的呼吸事件发生率没有差异。然而，在恢复室，被动吸烟者的血氧饱和度下降明显更常见（p < 0.02）。这与儿童接触的个体吸烟的累积数量有关（p < 0.05）。碳氧血红蛋白水平和家庭住址均不能预测血氧饱和度下降。本研究表明，被动吸烟会导致儿童全身麻醉术后动脉血氧饱和度下降。
