Huang Y C, Lin T Y, Wong K S, Chiu C H
Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan ROC.
J Formos Med Assoc. 1996 May;95(5):393-5.
We report a typical case of congenital varicella syndrome following a maternal varicella infection during the 10th week of pregnancy. The presenting symptoms in the small gestational age baby were: cicatricial skin lesion, Horner's syndrome,dysphagia with resulting aspiration pneumonia and delayed developmental milestones. Serologic studies revealed persistence of varicella zoster virus IgG for at least 10 months. Although congenital varicella syndrome is rare, it should be kept in mind when counseling families where maternal varicella infection has occurred during the first 20 weeks of gestation. A maternal history of varicella infection, typical manifestations and serologic proof are crucial in the diagnosis of congenital varicella syndrome.
我们报告了一例典型的先天性水痘综合征病例，该病例是由于母亲在妊娠第10周时感染水痘所致。这位小孕周婴儿的临床表现为：瘢痕性皮肤损害、霍纳综合征、吞咽困难并由此导致吸入性肺炎以及发育里程碑延迟。血清学研究显示水痘带状疱疹病毒IgG持续存在至少10个月。尽管先天性水痘综合征很罕见，但在为妊娠前20周内母亲发生水痘感染的家庭提供咨询时应予以考虑。母亲的水痘感染病史、典型表现以及血清学证据对先天性水痘综合征的诊断至关重要。
