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改良布莱洛克-陶西格分流术:是否进行肝素化?

Modified Blalock-Taussig shunts: to heparinize or not to heparinize?

作者信息

Mullen J C, Lemermeyer G, Bentley M J

机构信息

Division of Cardiothoracic Surgery, University of Alberta, Edmonton.

出版信息

Can J Cardiol. 1996 Jul;12(7):645-7.

PMID:8689534
Abstract

OBJECTIVE

To demonstrate shunt function of modified Blalock-Taussig Shunts (MBTSs) when no heparin is administered postoperatively.

PATIENTS AND INTERVENTIONS

Twenty-four MBTSs were performed on 23 children with various congenital heart problems needing palliation before the primary repair could be completed. A single low dose of heparin was given intraoperatively and no heparin was given postoperatively. Patients were evaluated for shunt patency, bleeding problems and the incidence of significant seromas at the graft site.

MAIN RESULTS

There was one perioperative death and no incidence of early shunt failure. Two children died from causes unrelated to shunt function. There were no postoperative bleeding difficulties (no reoperations), and no seromas surrounding the grafts. Late follow-up (mean 18 +/- 1 months) revealed no shunt failure.

CONCLUSIONS

Avoidance of heparin after an MBTS procedure is a safe practice and may reduce bleeding problems and the incidence of significant seromas surrounding the graft. Postoperative shunt thrombosis is more likely related to intraoperative technical difficulty or extremely small pulmonary artery size.

摘要

目的

证明在术后不使用肝素的情况下改良布莱洛克-陶西格分流术(MBTS)的分流功能。

患者与干预措施

对23例患有各种先天性心脏问题、在完成初次修复前需要姑息治疗的儿童实施了24次MBTS。术中给予单次低剂量肝素,术后不给予肝素。对患者的分流通畅情况、出血问题以及移植部位明显血清肿的发生率进行评估。

主要结果

围手术期有1例死亡,无早期分流失败的情况。2名儿童死于与分流功能无关的原因。无术后出血困难(无需再次手术),且移植部位周围无血清肿。晚期随访(平均18±1个月)显示无分流失败。

结论

MBTS术后避免使用肝素是一种安全的做法,可能会减少出血问题以及移植部位周围明显血清肿的发生率。术后分流血栓形成更可能与术中技术难度或肺动脉尺寸极小有关。

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