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环形损害中的混合临床与组织病理学模式:环形弹性组织溶解性巨细胞肉芽肿与环状肉芽肿之间的重叠?

Hybrid Clinical and Histopathological Pattern in Annular Lesions: An Overlap between Annular Elastolytic Giant Cell Granuloma and Granuloma Annulare?

作者信息

de Oliveira Felipe Ladeira, de Barros Silveira Luisa Kelmer Côrtes, Machado Alice de Miranda, Nery José Augusto da Costa

机构信息

Fundação Oswaldo Cruz (FIOCRUZ), Avenida Brasil, 4365 Manguinhos, 21040-360 Rio de Janeiro, RJ, Brazil.

出版信息

Case Rep Dermatol Med. 2012;2012:102915. doi: 10.1155/2012/102915. Epub 2012 Oct 15.

Abstract

Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of unclear pathogenesis which belongs to the group of disorders in the skin and elastic fibers with similar clinical features of granuloma annulare (GA). This case report is intended to describe a rare hybrid pattern in histopathology demonstrating coexistence of AEGCG and GA. An endocrine disease, such as diabetes mellitus (DM), could contribute to the coexistence of both lesions, and this possibility must be included in the medical investigation.

摘要

环状弹性组织溶解性巨细胞肉芽肿(AEGCG)是一种发病机制不明的罕见肉芽肿性皮肤病,属于皮肤和弹性纤维疾病组,具有与环状肉芽肿(GA)相似的临床特征。本病例报告旨在描述一种罕见的组织病理学混合模式,显示AEGCG和GA共存。内分泌疾病,如糖尿病(DM),可能导致两种病变共存,在医学检查中必须考虑到这种可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4065/3505946/7db23df2b0bc/CRIM.DM2012-102915.001.jpg

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