Nyamekye I, Lui D, Thomas S, Costa D, Bearn P, Raphael M, Adiseshiah M, Bishop C
UCL Hospitals NHS Trust, Vascular Unit, Middlesex Hospital, London, UK.
Clin Radiol. 1996 Jul;51(7):507-10. doi: 10.1016/s0009-9260(96)80192-9.
We assessed prospectively the significance of 111indium labelled platelet accumulation following angioplasty procedures in 12 patients (9 femoral angioplasties (2 laser, 1 atherectomy) and 3 iliac stents). Autologous 111indium labelled platelets were re-injected immediately after angioplasty. Radioactivity was measured over treated and reference sites, by single probe and gamma camera, and expressed as a radioactivity ratio (RR). All patients had duplex ultrasound assessment and occlusions were confirmed by arteriography. RR was always raised after angioplasty. Three patients who had acute occlusions showed markedly raised average RRs (significant at 99% ANOVA). RR was not raised after laser assisted angioplasty, however, our numbers were small. 111Indium platelet radioactivity did not predict subsequent occlusion after angioplasty but effectively detected existing acute post-angioplasty occlusions.
我们前瞻性地评估了12例患者（9例股动脉血管成形术（2例激光血管成形术，1例斑块旋切术）和3例髂动脉支架置入术）血管成形术后铟-111标记血小板聚集的意义。血管成形术后立即重新注入自体铟-111标记血小板。通过单探头和γ相机在治疗部位和对照部位测量放射性，并表示为放射性比值（RR）。所有患者均接受了双功超声评估，闭塞情况通过动脉造影得以证实。血管成形术后RR总是升高。3例发生急性闭塞的患者平均RR显著升高（方差分析在99%水平有显著性）。然而，激光辅助血管成形术后RR未升高，不过我们的样本量较小。铟-111血小板放射性不能预测血管成形术后的后续闭塞，但能有效检测出血管成形术后现有的急性闭塞。
