Jakobiec F A, Yanoff M, Mottow L, Anker P, Jones I S
Am J Ophthalmol. 1977 Jun;83(6):884-91. doi: 10.1016/0002-9394(77)90920-5.
Two middle-aged patients developed pigmented intrastromal iris nevi and an associated loss of the surrounding iris stromal markings suggestive of a surface iris membrane. Because of the fear of malignant melanoma with superficial growth, we excised the lesions. Histopathologic examination of the specimens revealed that the pigmented lesions were benign iris nevi and that the surrounding membrane was caused by endothelial cell growth onto the iris from peripheral anterior synechiae. These synechiae occurred anterior to Schwalbe's line in the same sector as the nevi and had been noted preoperatively at gonioscopic examination, but their diagnostic significance was not appreciated.
两名中年患者出现了基质内色素性虹膜痣，并伴有周围虹膜基质纹的缺失，提示存在虹膜表面膜。由于担心发生浅表生长的恶性黑色素瘤，我们切除了病变。标本的组织病理学检查显示，色素性病变为良性虹膜痣，周围的膜是由周边前粘连处的内皮细胞向虹膜生长所致。这些粘连发生在Schwalbe线前方，与痣位于同一象限，术前房角镜检查时已被发现，但未认识到其诊断意义。
