Abdel-Malek S, Bastien J W, Mahler W F, Jia Q, Reinecke M G, Robinson W E, Shu Y, Zalles-Asin J
Department of Chemistry, Texas Christian University (TCU), Fort Worth 76129, USA.
J Ethnopharmacol. 1996 Mar;50(3):157-66. doi: 10.1016/0378-8741(96)01380-3.
Aqueous, organic and alcoholic extracts of over 100 samples of 60 species of Kallawaya medicinal herbs representing 30 plant families were assayed to compare their toxicity and ability to protect MT-2 T-lymphoblastoid cells from the cytopathic effect of human immunodeficiency virus (HIV). The results are reported as a therapeutic index (TI) which was > 25 for eighteen species, including seven > 50 and one > 100. The anti-HIV activity resided primarily in the aqueous rather than in the organic extracts and was concentrated in plants used in ethnomedicine to treat lung and liver diseases.
对代表30个植物科的60种卡拉瓦亚药用植物的100多个样本的水提取物、有机提取物和酒精提取物进行了分析,以比较它们的毒性以及保护MT-2 T淋巴母细胞免受人类免疫缺陷病毒(HIV)细胞病变效应影响的能力。结果以治疗指数(TI)表示,18种植物的治疗指数>25,其中7种>50,1种>100。抗HIV活性主要存在于水提取物而非有机提取物中,并且集中在用于民族医学治疗肺部和肝脏疾病的植物中。