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[使用快速二维快速低角度激发序列对阻塞性睡眠呼吸暂停患者咽部进行功能磁共振成像]

[Functional MRI of the pharynx in obstructive sleep apnea using rapid 2D FLASH sequences].

作者信息

Jäger L, Günther E, Gauger J, Nitz W, Kastenbauer E, Reiser M

机构信息

Institut für Radiologische Diagnostik, Klinikum Grosshadern der Ludwig-Maximilians-Universität München.

出版信息

Radiologe. 1996 Mar;36(3):245-53. doi: 10.1007/s001170050068.

Abstract

Functional imaging of the pharynx used to be the domain of cineradiography, CT and ultrafast CT. The development of modern MRI techniques led to new access to functional disorders of the pharynx. The aim of this study was to implement a new MRI technique to examine oropharyngeal obstructive mechanisms in patients with obstructive sleep apnea (OSA). Sixteen patients suffering from OSA and 6 healthy volunteers were examined on a 1.5 T whole-body imager ("Vision", Siemens, Erlangen Medical Engineering, Germany) using a circular polarized head coil. Imaging was performed with 2D flash sequences in midsagittal and axial planes. Patients and volunteers were asked to breathe normally through the nose and to simulate snoring and the Mueller maneuver during magnetic resonance imaging (MRI). Prior to MRI, all patients underwent an ear, nose and throat (ENT) examination, functional fiberoptic nasopharyngoscopy and polysomnography. A temporal resolution of 6 images/s and an in-plane resolution of 2.67 x 1.8 mm were achieved. The mobility of the tongue, soft palate and pharyngeal surface could be clearly delineated. The MRI findings correlated well with the clinical examinations. We propose ultrafast MRI as a reliable and non-invasive method of evaluating pharyngeal obstruction and their levels.

摘要

咽部的功能成像过去一直是电影放射摄影、CT和超速CT的领域。现代MRI技术的发展为研究咽部功能障碍带来了新途径。本研究的目的是应用一种新的MRI技术来检查阻塞性睡眠呼吸暂停(OSA)患者的口咽阻塞机制。16例OSA患者和6名健康志愿者在一台1.5T全身成像仪(“Vision”,西门子,德国埃尔朗根医学工程公司)上接受检查,使用圆极化头部线圈。在矢状面和轴位平面用二维快速小角度激发序列进行成像。要求患者和志愿者在磁共振成像(MRI)期间通过鼻子正常呼吸,并模拟打鼾和米勒动作。在MRI检查前,所有患者均接受了耳鼻喉(ENT)检查、功能性纤维鼻咽镜检查和多导睡眠图检查。实现了6帧/秒的时间分辨率和2.67×1.8mm的平面分辨率。可以清晰地描绘出舌头、软腭和咽表面的活动情况。MRI检查结果与临床检查结果相关性良好。我们建议将超速MRI作为评估咽部阻塞及其程度的一种可靠且无创的方法。

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