Abeledo Mezquita G, Otero Reigada M C
An Esp Pediatr. 1977 Feb;10(2):167-70.
Five children with tuberculosis were treated with isoniazid (20 mg./Kg./day) and rifampin (15 mg./Kg./day). After five to twenty seven days of treatment they presented anorexia, vomiting and jaundice. Hepatomegaly was found in two of them. High indirect bilirubin, S.G.O.T. and S.G.P.T. and low prothrombin levels were present in all of them. Eight to thirty one days after withdrawal of rifampin, all patients were well and their laboratory data was normal.
五名患有结核病的儿童接受了异烟肼（20毫克/千克/天）和利福平（15毫克/千克/天）治疗。治疗五至二十七天后，他们出现了厌食、呕吐和黄疸症状。其中两名儿童出现肝脏肿大。所有儿童均出现高间接胆红素、谷草转氨酶和谷丙转氨酶水平以及低凝血酶原水平。停用利福平八至三十一天后，所有患者情况良好，实验室数据正常。
