注射丙泊酚期间温度对疼痛的影响。

The effect of temperature upon pain during injection of propofol.

作者信息

Fletcher G C, Gillespie J A, Davidson J A

机构信息

Clinical Shock Study Group, Western Infirmary, Glasgow.

出版信息

Anaesthesia. 1996 May;51(5):498-9. doi: 10.1111/j.1365-2044.1996.tb07802.x.

DOI:10.1111/j.1365-2044.1996.tb07802.x

PMID:8694170

Abstract

Propofol has been shown to cause pain on injection. This study investigated the effect of warming propofol to 37 degrees C on the pain of intravenous injection. One hundred and one women on outpatient gynaecology lists were allocated to receive propofol either at room temperature or at 37 degrees C. Warming propofol decreased the incidence of pain on injection by 37% (p < 0.001), and also decreased the severity of pain reported by patients (p < 0.001). We conclude that warming propofol to 37 degrees C provides a simple and safe method of reducing the incidence of pain on injection without the addition of other agents.

摘要

已证实丙泊酚注射时会引起疼痛。本研究调查了将丙泊酚加热至37摄氏度对静脉注射疼痛的影响。将101名妇科门诊名单上的女性分配接受室温下或37摄氏度的丙泊酚。加热丙泊酚可使注射时的疼痛发生率降低37%（p<0.001），并且还降低了患者报告的疼痛严重程度（p<0.001）。我们得出结论，将丙泊酚加热至37摄氏度提供了一种简单且安全的方法，可在不添加其他药物的情况下降低注射时的疼痛发生率。