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肾小管酸中毒。病理生理学与诊断。

Renal tubular acidosis. Pathophysiology and diagnosis.

作者信息

Smulders Y M, Frissen P H, Slaats E H, Silberbusch J

机构信息

Department of Internal Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.

出版信息

Arch Intern Med. 1996;156(15):1629-36.

PMID:8694660
Abstract

The pathophysiology of renal tubular acidosis is slowly being unraveled, which has implications for the traditional classification of the condition. Nonetheless, the diagnosis of renal tubular acidosis is still easy to establish, and identification of the specific pathophysiological subtype is relatively straightforward. The diagnostic information required usually includes only urinary pH and sodium, potassium, and chloride concentrations and serum potassium level. The urinary pH is not a diagnostic test for renal tubular acidosis, but it serves to distinguish between the various subtypes.

摘要

肾小管酸中毒的病理生理学正在逐步被揭示,这对该病症的传统分类有重要意义。尽管如此,肾小管酸中毒的诊断仍然很容易确立,而且确定具体的病理生理亚型相对简单。通常所需的诊断信息仅包括尿液pH值、钠、钾、氯浓度以及血清钾水平。尿液pH值并非肾小管酸中毒的诊断性检测指标,但它有助于区分不同的亚型。

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