Hörmansdorfer S, Bauer J
Lehrstuhl für Tierhygiene der Technischen Universität München.
Berl Munch Tierarztl Wochenschr. 1996 May;109(5):168-71.
The sensibility of 375 pasteurellae of bovine origin (215 pasteurella multocida--and 160 pasteurella haemolytica--strains) was examined against 16 antibiotics or chemotherapeutics by agar diffusion technique. A great part of the strains was resistant to oxacillin (41,18%), tylosin (79,14%), streptomycin (53,21%), sulfonamides (57,33%) and tetracycline (47,20%). Only a few resistant strains were found for cephalothin (5,07%), polymyxin B (0,27%) and enrofloxacin (0,53%). While 16,27% of all isolates were resistant to chloramphenicol, 100% of the pasteurella strains proved to be sensible to its structural analogon florfenicol. This is affirmed by the low minimal inhibitory concentrations (0,25-1,0 micrograms/ml) of this antibiotic.
采用琼脂扩散技术检测了375株牛源巴斯德菌(215株多杀性巴氏杆菌和160株溶血巴氏杆菌)对16种抗生素或化学治疗剂的敏感性。大部分菌株对苯唑西林(41.18%)、泰乐菌素(79.14%)、链霉素(53.21%)、磺胺类药物(57.33%)和四环素(47.20%)耐药。仅发现少数菌株对头孢噻吩(5.07%)、多粘菌素B(0.27%)和恩诺沙星(0.53%)耐药。虽然所有分离株中有16.27%对氯霉素耐药,但100%的巴氏杆菌菌株对其结构类似物氟苯尼考敏感。该抗生素的最低抑菌浓度较低(0.25 - 1.0微克/毫升),证实了这一点。