多杀巴斯德氏菌中新的质粒携带抗生素抗性基因簇
New plasmid-borne antibiotic resistance gene cluster in Pasteurella multocida.
作者信息
Kehrenberg Corinna, Tham Nga Thi Thu, Schwarz Stefan
机构信息
Institut für Tierzucht, Bundesforschungsanstalt für Landwirtschaft (FAL), 31535 Neustadt-Mariensee, Germany.
出版信息
Antimicrob Agents Chemother. 2003 Sep;47(9):2978-80. doi: 10.1128/AAC.47.9.2978-2980.2003.
Abstract
A new antibiotic resistance gene cluster comprising genes for sulfonamide (sul2), streptomycin (strA-strB), and tetracycline [tetR-tet(H)] resistance was detected on plasmid pVM111 from Pasteurella multocida. The tetR-tet(H) gene region was inserted between sul2 and strA, possibly by illegitimate recombination. Two potential recombination sites of 18 and 25 bp were identified.
摘要
在多杀性巴氏杆菌的质粒pVM111上检测到一个新的抗生素抗性基因簇，其包含磺胺类（sul2）、链霉素（strA-strB）和四环素[tetR-tet(H)]抗性基因。tetR-tet(H)基因区域可能通过非法重组插入到sul2和strA之间。鉴定出两个18 bp和25 bp的潜在重组位点。
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