Tn5706，一种来自多杀巴斯德菌的介导四环素抗性的转座子样元件。
Tn5706, a transposon-like element from Pasteurella multocida mediating tetracycline resistance.
作者信息
Kehrenberg C, Werckenthin C, Schwarz S
机构信息
Institut für Tierzucht und Tierverhalten der Bundesforschungsanstalt für Landwirtschaft Braunschweig-Völkenrode, 29223 Celle, Germany.
出版信息
Antimicrob Agents Chemother. 1998 Aug;42(8):2116-8. doi: 10.1128/AAC.42.8.2116.
Abstract
The 4,378-bp putative tetracycline resistance transposon Tn5706 of Pasteurella multocida consists of an internal tet(H)-tetR resistance gene region which is flanked by almost identical insertion elements, IS1596 and IS1597. Two reading frames for proteins of 70 and 228 amino acids were detected in each of these insertion sequence elements. The 228-amino-acid protein revealed homology to transposase proteins of gram-positive bacteria.
摘要
多杀巴斯德氏菌的4378碱基对推定四环素抗性转座子Tn5706由一个内部tet(H)-tetR抗性基因区域组成，该区域两侧是几乎相同的插入元件IS1596和IS1597。在这些插入序列元件的每一个中都检测到了两个分别编码70和228个氨基酸的蛋白质的阅读框。这种228个氨基酸的蛋白质与革兰氏阳性菌的转座酶蛋白具有同源性。
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