Sinha S M, Pasricha J S, Sharma R, Kandhari K C
Arch Dermatol. 1977 Jun;113(6):776-9.
Fifty-three patients having contact dermatitis on the fingertips showed positive patch tests with several vegetables the commonest being garlic, onion, tomato, and carrot in that order of frequency. Of several preparations, made from garlic onion, tomato, and carrot, the juices used as such gave the maximum number of positive patch test reactions. Lyophilization of the juices led to false-negative patch tests in some cases. Patch tests in the controls were positive in some cases but these were probably cases of latent hypersensitivity, because some of them, like the patients, showed positive reactions even with the diluted juices. The antigens in garlic and onion were extractable in water, ether, acetone, or alcohol and were also present in the essential oils of these vegetables. Infrared spectra of the essential oils of garlic and onion were similar and showed straight chain acids, esters, and methylene groups. Clinically, there was no suggestion of cross-sensitivity between onion and garlic.
53例指尖患接触性皮炎的患者对几种蔬菜斑贴试验呈阳性，最常见的依次为大蒜、洋葱、番茄和胡萝卜。用大蒜、洋葱、番茄和胡萝卜制成的几种制剂中，直接使用的汁液产生的斑贴试验阳性反应最多。汁液冻干在某些情况下会导致斑贴试验假阴性。对照组的斑贴试验在某些情况下呈阳性，但这些可能是潜在超敏反应的病例，因为其中一些人和患者一样，即使使用稀释汁液也呈阳性反应。大蒜和洋葱中的抗原可溶于水、乙醚、丙酮或酒精，这些蔬菜的精油中也含有这些抗原。大蒜和洋葱精油的红外光谱相似，显示出直链酸、酯和亚甲基。临床上，没有迹象表明洋葱和大蒜之间存在交叉敏感性。
