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解释酒精滥用治疗后的戒酒率:对患者、研究设计和治疗效果的定量综合分析。

Explaining abstinence rates following treatment for alcohol abuse: a quantitative synthesis of patient, research design and treatment effects.

作者信息

Monahan S C, Finney J W

机构信息

Center for Health Care Evaluation, VA-Palo Alto Health Care System, USA.

出版信息

Addiction. 1996 Jun;91(6):787-805. doi: 10.1046/j.1360-0443.1996.9167876.x.

Abstract

We examined the relationships of treatment, patient and research design characteristics to treatment outcome (i.e. abstinence rates) in a sample of 150 treatment conditions drawn from 100 alcohol treatment outcome studies published between 1980 and 1992. Treatment characteristics were related to abstinence rates: more intensive treatments had higher abstinence rates than less intensive treatments, whereas treatments with an expressed goal other than abstinence had lower abstinence rates than treatments with an abstinence goal. When the public vs. private ownership status of the treatment facility was taken into account, the presence of behavioral elements in the treatment condition also was related to higher abstinence rates. Because of inconsistent reporting in primary studies, we assessed the effects of only one patient pre-treatment characteristic; treatment conditions with a higher proportion of socially stable patients had better outcomes. Research design characteristics were also related to abstinence rates. Treatment conditions with shorter follow-ups and treatments drawn from studies that did not use criteria to exclude more impaired subjects had better outcomes. We discuss possible reasons why our findings regarding the effects of treatment intensity and the use of exclusionary criteria differ from those in previous reviews.

摘要

我们从1980年至1992年发表的100项酒精治疗结果研究中抽取了150个治疗条件样本,研究了治疗、患者及研究设计特征与治疗结果(即戒酒率)之间的关系。治疗特征与戒酒率相关:更强化的治疗比不太强化的治疗有更高的戒酒率,而目标不是戒酒的治疗比以戒酒为目标的治疗有更低的戒酒率。当考虑治疗机构的公立与私立所有权状况时,治疗条件中行为要素的存在也与更高的戒酒率相关。由于原始研究报告不一致,我们仅评估了一个患者治疗前特征的影响;社会稳定患者比例较高的治疗条件有更好的结果。研究设计特征也与戒酒率相关。随访时间较短的治疗条件以及来自未使用标准排除受损程度更高受试者的研究中的治疗有更好的结果。我们讨论了为何我们关于治疗强度和排除标准影响的研究结果与之前综述不同的可能原因。

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