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酒精中毒短期戒酒的预后效度

Prognostic validity of short-term abstinence in alcoholism.

作者信息

Yates W R, Reed D A, Booth B M, Masterson B J, Brown K

机构信息

Department of Psychiatry, University of Iowa College of Medicine, Iowa City.

出版信息

Alcohol Clin Exp Res. 1994 Apr;18(2):280-3. doi: 10.1111/j.1530-0277.1994.tb00015.x.

Abstract

A demonstrated period of abstinence is often viewed as a good prognostic sign in alcoholism. For example, short-term abstinence is one factor often considered important as a selection criteria for alcoholics who are being evaluated as liver transplant candidates. However, the prognostic validity of short-term abstinence is unclear. We evaluated the effects of 3 and 6 months of abstinence on readmission rates in a series of 299 alcoholics following discharge from inpatient treatment. Readmission rates were stratified using a 3-factor model of alcoholism severity. This 3-factor model defined groups with 1-year readmission rates, ranging from 15.8% to 62.7%. Short-term abstinence did not have strong effects on readmission rates for the most severe alcoholics, nor did short-term abstinence produce clinically significant reduction for readmission rates for the least severe alcoholics. We conclude that short-term abstinence has minimal effect on prognosis for alcoholics with various levels of baseline severity.

摘要

在酒精中毒中,一段已证实的戒酒期通常被视为良好的预后标志。例如,短期戒酒是经常被认为作为评估肝移植候选者的酗酒者选择标准的一个重要因素。然而,短期戒酒的预后有效性尚不清楚。我们评估了299名酗酒者在住院治疗出院后3个月和6个月戒酒对再入院率的影响。再入院率使用酒精中毒严重程度的三因素模型进行分层。这个三因素模型定义了1年再入院率从15.8%到62.7%不等的组别。短期戒酒对最严重酗酒者的再入院率没有强烈影响,对于最不严重的酗酒者,短期戒酒也没有使再入院率产生临床上显著的降低。我们得出结论,短期戒酒对具有不同基线严重程度水平的酗酒者的预后影响极小。

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