Hammarström L E, Holmin T, Stridbeck H, Ihse I
Department of Surgery, University of Lund, Sweden.
Br J Surg. 1996 Jun;83(6):750-4. doi: 10.1002/bjs.1800830608.
The role of preoperative infusion cholangiography (PIC) before elective cholecystectomy has yet to be defined. Between 1985 and 1991 PIC was performed routinely in 694 patients with median (range) age of 52 (17-85) years with biliary calculus disease 1 or 4 days before elective cholecystectomy. Satisfactory opacification of the biliary system was achieved in 90.1 per cent and mild to moderate adverse reactions to the infusion of contrast medium occurred in 0.9 per cent of patients. Peroperative cholangiography (POC) in 43 of 499 patients with a normal PIC was normal. The presence of common bile duct stones was confirmed in 34 of 36 patients with prominent stones at bile duct exploration and in 8 of 26 with suspected stones at PIC. Bile duct dilatation (median diameter 10 mm) without concomitant stones was seen at PIC and confirmed at POC in 20 patients. Bile duct anomalies were found or suspected in 35 patients at PIC and were confirmed in six by POC (n = 5), or during the cholecystectomy making the anomaly incidence 0.9 per cent. Information provided by the PIC was not of crucial importance for safe execution of cholecystectomy in any patient, while a single (minor) bile duct lesion (1 of 694; 0.1 per cent) could be ascribed to severe pericholecystitis. The results of this study suggest that routine PIC is not warranted. However, PIC is an alternative to selective preoperative endoscopic retrograde cholangiography or selective POC. PIC needs to be supported by POC in approximately 20 per cent of patients (in case of absent or poor opacification of the bile ducts or suspicion of stones or anomalies at PIC).
择期胆囊切除术前行术中胆管造影(PIC)的作用尚未明确。1985年至1991年间,694例患有胆石症的患者在择期胆囊切除术1或4天前常规进行了PIC,患者年龄中位数(范围)为52岁(17 - 85岁)。90.1%的患者胆管系统造影满意,0.9%的患者对造影剂注入有轻度至中度不良反应。499例PIC正常的患者中有43例进行了术中胆管造影(POC),结果正常。36例胆管探查时发现明显结石的患者中有34例经证实存在胆总管结石,26例PIC怀疑有结石的患者中有8例经证实存在胆总管结石。20例患者在PIC时发现胆管扩张(中位数直径10mm)且无结石,POC证实了这一情况。35例患者在PIC时发现或怀疑有胆管异常,其中6例经POC(n = 5)或在胆囊切除术中得到证实,异常发生率为0.9%。PIC提供的信息对任何患者安全实施胆囊切除术并非至关重要,而1例(694例中的1例;0.1%)单一(轻微)胆管病变可归因于严重胆囊炎。本研究结果表明,常规PIC并无必要。然而,PIC是选择性术前内镜逆行胆管造影或选择性POC的替代方法。约20%的患者需要POC辅助PIC(如胆管造影不显影或显影不佳,或PIC怀疑有结石或异常)。