Achterberg V, Meyer-Ingold W
J Wound Care. 1996 Feb;5(2):79-82.
An in vitro approach was used to obtain information about the compatibility of hydroactive dressing materials with the serum proteins which are thought to be relevant to wound healing. Artificial wound fluid was incubated with different hydroactive dressings (Cutinova hydro, Varihesive E, Comfeel Ulcer Dressing and Allevyn), and concentrations of total protein, albumin, immunoglobulin and growth factors were measured after one day of incubation. Cutinova hydro and Allevyn absorbed considerable amounts of fluid. Fluid uptake was lower for the hydrocolloid dressings. An unexpected finding was that Cutinova hydro showed an approximately two-fold increase over control values in the concentration of all proteins tested, indicating a selective absorption of water by this dressing. For the other dressings tested, zero or very low absorption of proteins was found, indicating a basically satisfactory protein compatibility.
采用体外实验方法获取有关水活性敷料材料与血清蛋白相容性的信息，血清蛋白被认为与伤口愈合相关。将人工伤口液与不同的水活性敷料（Cutinova hydro、Varihesive E、Comfeel溃疡敷料和Allevyn）一起孵育，孵育一天后测量总蛋白、白蛋白、免疫球蛋白和生长因子的浓度。Cutinova hydro和Allevyn吸收了大量液体。水胶体敷料的液体吸收量较低。一个意外发现是，Cutinova hydro测试的所有蛋白质浓度比对照值增加了约两倍，表明该敷料对水有选择性吸收。对于其他测试的敷料，发现蛋白质吸收为零或非常低，表明蛋白质相容性基本令人满意。
