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1
Post-stent management with a pneumatic groin compression device and self injected low molecular weight heparin.使用气动腹股沟压迫装置和自我注射低分子量肝素进行支架置入术后管理。
Heart. 1996 Jun;75(6):588-90. doi: 10.1136/hrt.75.6.588.
2
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Cathet Cardiovasc Diagn. 1996 Nov;39(3):224-9. doi: 10.1002/(SICI)1097-0304(199611)39:3<224::AID-CCD3>3.0.CO;2-G.
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Low-molecular-weight heparins for the treatment of deep-vein thrombosis.低分子量肝素用于治疗深静脉血栓形成。
Clin Pharm. 1993 Dec;12(12):892-9.
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Low molecular weight heparin treatment of venous thromboembolism.低分子量肝素治疗静脉血栓栓塞症。
Prog Cardiovasc Dis. 1994 Sep-Oct;37(2):71-8. doi: 10.1016/s0033-0620(05)80043-x.
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A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease. Stent Restenosis Study Investigators.冠状动脉支架置入术与球囊血管成形术治疗冠状动脉疾病的随机对照研究。支架再狭窄研究组。
N Engl J Med. 1994 Aug 25;331(8):496-501. doi: 10.1056/NEJM199408253310802.
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A comparison of balloon-expandable-stent implantation with balloon angioplasty in patients with coronary artery disease. Benestent Study Group.冠状动脉疾病患者中球囊扩张式支架植入术与球囊血管成形术的比较。贝内斯特恩研究小组。
N Engl J Med. 1994 Aug 25;331(8):489-95. doi: 10.1056/NEJM199408253310801.
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Mechanisms for the antithrombotic activity in man of low molecular weight heparins (LMWHs).
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Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin.接受低分子量肝素或普通肝素治疗的患者发生肝素诱导的血小板减少症。
N Engl J Med. 1995 May 18;332(20):1330-5. doi: 10.1056/NEJM199505183322003.
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Prophylaxis of postoperative thromboembolism with low molecular weight heparins.低分子量肝素预防术后血栓栓塞
Br J Surg. 1993 Jun;80(6):689-704. doi: 10.1002/bjs.1800800607.
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Rationale for development of low-molecular-weight heparins and their clinical potential in the prevention of postoperative venous thrombosis.低分子量肝素的研发原理及其在预防术后静脉血栓形成中的临床潜力。
Am J Surg. 1991 Apr;161(4):512-8. doi: 10.1016/0002-9610(91)91123-z.

使用气动腹股沟压迫装置和自我注射低分子量肝素进行支架置入术后管理。

Post-stent management with a pneumatic groin compression device and self injected low molecular weight heparin.

作者信息

Stables R H, Sigwart U

机构信息

Department of Invasive Cardiology, Royal Brompton Hospital, London.

出版信息

Heart. 1996 Jun;75(6):588-90. doi: 10.1136/hrt.75.6.588.

DOI:10.1136/hrt.75.6.588
PMID:8697162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC484382/
Abstract

BACKGROUND

The benefits of intracoronary stent implantation are offset by an increased risk of complications at the arterial puncture site and a prolonged hospital stay. Much of this morbidity can be attributed to the generally perceived need to achieve systemic anticoagulation after stent implantation.

AIM

To test a simplified protocol for post-stent management using the Femostop pneumatic groin compression device and low molecular weight (fractionated) heparin (LMWH) administered by subcutaneous injection.

PATIENTS

A case series of 100 consecutive patients, with stable angina pectoris, undergoing coronary stenting for a suboptimal result after conventional balloon angioplasty.

METHODS

All patients were managed with a new post-stent protocol using the Femostop pneumatic groin compression device and LMWH. The incidence of complications and the length of hospital stay were recorded.

RESULTS

The clinical course was uncomplicated in 92 patients and their discharge from hospital was achieved on the first post-procedural day for 44 patients and on the second for the remaining 48. The rate of vascular or bleeding complications was 6%.

CONCLUSIONS

LMWH administered by subcutaneous injection may provide a practical and effective alternative to the use of intravenous heparin when systemic anticoagulation is used after stent implantation.

摘要

背景

冠状动脉内支架植入的益处被动脉穿刺部位并发症风险增加和住院时间延长所抵消。这种发病率的增加很大程度上可归因于支架植入后普遍认为需要进行全身抗凝。

目的

使用Femostop气动腹股沟压迫装置和皮下注射低分子量(分馏)肝素(LMWH)来测试一种简化的支架置入后管理方案。

患者

一个包含100例连续患者的病例系列,这些患者患有稳定型心绞痛,在常规球囊血管成形术后冠状动脉支架置入效果欠佳。

方法

所有患者均采用使用Femostop气动腹股沟压迫装置和LMWH的新的支架置入后方案进行管理。记录并发症发生率和住院时间。

结果

92例患者临床过程无并发症,44例患者在术后第一天出院,其余48例在第二天出院。血管或出血并发症发生率为6%。

结论

当支架植入后使用全身抗凝时,皮下注射LMWH可能是使用静脉肝素的一种实用且有效的替代方法。