Nóvak E M, Werneck L C, Mora A H
Arq Neuropsiquiatr. 1977 Jun;35(2):146-50. doi: 10.1590/s0004-282x1977000200007.
A case of Behcet's disease in a pregnant patient is reported. The patient showed central nervous system involvement as well eyes, mouth, external genitalia and skin lesions. The neurological signs were cranial nerves palsies and pyramidal tract involvement. The cerebrospinal fluid showed hypercytosis and hyper-gammaglobulin. The patient was treated with sistemic dexamethasone and eye drops of atropine and fluorometolone. The delivery was by elective cesarean section at 8th and a half month of pregnancy. In the examination of 6 month-old the infant was normal. The patient improved but remained with important visual loss. The authors think that the pregnancy helped the partial recovery and the good evolution; similar cases have been reported in the literature. A rapid review about the central nervous system involvement and treatment of Behçet's disease is made.
本文报告了一例妊娠合并白塞病的病例。该患者表现为中枢神经系统受累,同时伴有眼部、口腔、外生殖器及皮肤病变。神经学体征为颅神经麻痹和锥体束受累。脑脊液显示细胞增多和γ球蛋白升高。患者接受了全身地塞米松治疗以及阿托品和氟米龙滴眼液治疗。妊娠8个半月时行选择性剖宫产。6个月大婴儿检查正常。患者病情有所改善,但仍有严重视力丧失。作者认为妊娠有助于部分恢复及良好转归;文献中已有类似病例报道。本文还对白塞病中枢神经系统受累情况及治疗进行了简要综述。