Johnson D H, Cunha B A
Infectious Disease Division, Winthrop-University Hospital, Mineola, NY, USA.
Infect Dis Clin North Am. 1996 Mar;10(1):85-91. doi: 10.1016/s0891-5520(05)70287-7.
Drug fever is the febrile response to a drug without cutaneous manifestations. Although the exact incidence of drug fever remains unknown, it has been estimated to occur in approximately 10% of inpatients. The recognition of drug fever is of great clinical importance because, if drug fever is not recognized diagnostically, patients may be subjected to prolonged hospitalization and unnecessary testing or medications. Early diagnosis and treatment of drug fevers are essential in maintaining cost-effective, high-quality medical care.
药物热是指对药物产生的发热反应，且无皮肤表现。尽管药物热的确切发病率尚不清楚，但据估计约10%的住院患者会出现药物热。认识药物热具有重要的临床意义，因为如果不能诊断出药物热，患者可能会面临延长住院时间以及接受不必要的检查或用药。早期诊断和治疗药物热对于维持具有成本效益的高质量医疗护理至关重要。
