番荔枝碱和刺桐碱，两种来自刺番荔枝的儿茶酚类小檗碱。

Pessoine and spinosine, two catecholic berbines from Annona spinescens.

作者信息

Queiroz E F, Roblot F, Cavé A, Paulo M Q, Fournet A

机构信息

Laboratoire de Pharmacognosie, U.R.A. 1843 CNRS (BIOCIS), Faculté de Pharmacie. Chatenay-Malabry, France.

出版信息

J Nat Prod. 1996 Apr;59(4):438-40. doi: 10.1021/np960223w.

DOI:10.1021/np960223w

PMID:8699188

Abstract

The trunk bark and roots of Annona spinescens have been investigated for their alkaloid content. Two new berbine alkaloids, pessoine (1) and spinosine (2), have been isolated from the bark, and their structures were elucidated by spectroscopic methods. Eight known isoquinoline alkaloids were also obtained. The trypanocidal and antileishmanial activities of these isolated compounds have been investigated.

摘要

对刺番荔枝的树干树皮和根部进行了生物碱含量研究。从树皮中分离出了两种新的小檗碱生物碱，佩索因（1）和刺番荔枝碱（2），并通过光谱方法阐明了它们的结构。还获得了八种已知的异喹啉生物碱。对这些分离出的化合物的杀锥虫和抗利什曼原虫活性进行了研究。