Eggli P S, Graber W
Institute of Anatomy, University of Bern, Switzerland.
J Neurocytol. 1996 Feb;25(2):79-87. doi: 10.1007/BF02284787.
A potential association between hyaluronan and unmyelinated nerve fibres in the PNS (rat skin and iris) and CNS (rat retinal inner plexiform and nerve fibre layers) was investigated at the ultrastructural level using two different hyaluronan-binding probes (link protein-gold and aggrecan-gold). Neuronal and glial cell plasma membranes, as well as the periaxonal space in between, were specifically labelled, suggesting that hyaluronan is secreted by these cells and utilized locally. Intracelluarly, weak labelling of mitochondrial profiles was observed.
利用两种不同的透明质酸结合探针（连接蛋白-金和聚集蛋白聚糖-金），在超微结构水平上研究了周围神经系统（大鼠皮肤和虹膜）和中枢神经系统（大鼠视网膜内网状层和神经纤维层）中透明质酸与无髓神经纤维之间的潜在关联。神经元和神经胶质细胞质膜以及其间的轴突周围间隙被特异性标记，表明透明质酸由这些细胞分泌并在局部发挥作用。在细胞内，观察到线粒体轮廓有微弱标记。
