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一种用于在同时记录多条多单元神经纤维时进行实时脉冲鉴别(尖峰鉴别)的神经网络方法。

A neural network approach to real-time spike discrimination during simultaneous recording from several multi-unit nerve filaments.

作者信息

Ohberg F, Johansson H, Bergenheim M, Pedersen J, Djupsjöbacka M

机构信息

Division of Work Physiology, National Institute of Occupational Health, Umeå, Sweden.

出版信息

J Neurosci Methods. 1996 Feb;64(2):181-7. doi: 10.1016/0165-0270(95)00132-8.

DOI:10.1016/0165-0270(95)00132-8
PMID:8699879
Abstract

A multi-channel, real-time, unsupervised spike discriminator was developed in order to reconstruct single spike trains from several simultaneously recorded multi-unit nerve filaments. The program uses a Self Organising Map (SOM) algorithm for the classification of the spikes. In contrast to previous similar techniques, the described method is made for use on a PC, and the method may thus be implemented at relatively low cost. In order to test the accuracy of the program, a robustness test was performed, where noise with different RMS levels was superimposed on the spikes. Furthermore, the maximal classification rate was determined. The program is easy to use, since the only manual inputs needed are the voltage threshold for spike detection, and the number of units present in each recorded nerve filament.

摘要

为了从多个同时记录的多单元神经丝中重建单峰序列,开发了一种多通道、实时、无监督的峰值鉴别器。该程序使用自组织映射(SOM)算法对峰值进行分类。与以前的类似技术相比,所描述的方法适用于个人计算机,因此可以以相对较低的成本实现。为了测试该程序的准确性,进行了一项稳健性测试,将具有不同均方根(RMS)水平的噪声叠加在峰值上。此外,还确定了最大分类率。该程序易于使用,因为唯一需要的手动输入是峰值检测的电压阈值以及每个记录的神经丝中存在的单元数量。

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High-density microelectrode array recordings and real-time spike sorting for closed-loop experiments: an emerging technology to study neural plasticity.高密度微电极阵列记录和实时尖峰分类用于闭环实验:研究神经可塑性的新兴技术。
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利用调谐信息进行自动尖峰分类
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Traditional waveform based spike sorting yields biased rate code estimates.基于传统波形的尖峰分类会产生有偏差的速率编码估计。
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