Picton W, Clark C
Br J Dermatol. 1977 Mar;96(3):277-82. doi: 10.1111/j.1365-2133.1977.tb06137.x.
The effect of castration on the size of sebaceous glands of male hairless mice and male hairless hamsters was studied over a period of 4 weeks. Statistically significant decreases in the size of sebaceous glands were observed. The effects of intracutaneous injections of micronized crystalline suspensions of testosterone, testosterone propionate, testosterone phenylpropionate, testosterone decanoate and nandrolone phenylpropionate on the sebaceous glands of castrated hairless mice, castrated hairless hamsters and intact female hairless hamsters were studied over a period of one week. Highly significant increases in sebaceous gland volume were observed 6-7 days after treatment. The effects of subcutaneous and intracutaneous injections of micronized crystalline suspensions of testosterone on the sebaceous glands of intact male and female hairless hamsters were examined at sites local and distal to the injection. Increases in sebaceous gland volume were limited to local sites in the male but increases were observed locally and distally in the female. There was no difference between subcutaneous and intracutaneous injections.
在4周的时间内研究了去势对雄性无毛小鼠和雄性无毛仓鼠皮脂腺大小的影响。观察到皮脂腺大小有统计学意义的减小。在1周的时间内研究了皮内注射微粉化的睾酮、丙酸睾酮、苯丙酸睾酮、癸酸睾酮和苯丙酸诺龙结晶悬浮液对去势无毛小鼠、去势无毛仓鼠和完整雌性无毛仓鼠皮脂腺的影响。治疗后6 - 7天观察到皮脂腺体积有极显著增加。在完整的雄性和雌性无毛仓鼠的注射局部和远端部位，检查了皮下和皮内注射微粉化睾酮结晶悬浮液对皮脂腺的影响。皮脂腺体积的增加在雄性中仅限于局部部位，但在雌性中局部和远端均有增加。皮下注射和皮内注射之间没有差异。
