Lazarev A I, Prokopenko L G
Patol Fiziol Eksp Ter. 1995 Oct-Dec(4):18-21.
Potassium hyaluronate was found to suppress the development of a humoral response and delayed hypersensitivity, while hyaluronidase and the incubate of potassium hyaluronate and hyaluronidase enhanced the manifestations of the humoral response and delayed hypersensitivity. The suppressive effect of potassium hyaluronate was mediated by light erythrocytes, whereas the stimulating effect of hyaluronidase the incubates of potassium hyaluronate and hyaluronidase was mediated by heavy erythrocytes. In Staphylococcus infection, hyaluronidase and the incubates of potassium hyaluronate and hyaluronidase enhanced the development of a humoral response and failed to affect the manifestations of delayed hypersensitivity.
发现透明质酸钾可抑制体液反应和迟发型超敏反应的发展，而透明质酸酶以及透明质酸钾与透明质酸酶的孵育物则增强了体液反应和迟发型超敏反应的表现。透明质酸钾的抑制作用由轻度红细胞介导，而透明质酸酶以及透明质酸钾与透明质酸酶的孵育物的刺激作用则由重度红细胞介导。在葡萄球菌感染中，透明质酸酶以及透明质酸钾与透明质酸酶的孵育物增强了体液反应的发展，且未影响迟发型超敏反应的表现。
