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[无胸腺裸鼠造血的特征]

[Characteristics of hematopoiesis in athymic nude mice].

作者信息

Gol'dberg E D, Karpova G V, Novitskiĭ V V, Iunker V M, Morozkova T S

出版信息

Biull Eksp Biol Med. 1977 Apr;83(4):463-4.

PMID:870112
Abstract

The bone marrow, peripheral blood and spleen state was studied from the age aspect in Nude mice characterized by recessive nu mutation. A number of blood system peculiarities were revealed in homozygotic (nu/nu) mice by which they differed from the heterozygotic (nu/+) animals: low peripheral blood, bone marrow and spleen lymphocyte count, erythropoiesis depression in the bone marrow and erythroid element hyperplasia in the spleen.

摘要

从年龄方面研究了具有隐性裸突变特征的裸鼠的骨髓、外周血和脾脏状态。在纯合子(nu/nu)小鼠中发现了许多血液系统特性,这些特性使它们与杂合子(nu/+)动物不同:外周血、骨髓和脾脏淋巴细胞计数低,骨髓红细胞生成受抑制,脾脏红系成分增生。

相似文献

1
[Characteristics of hematopoiesis in athymic nude mice].[无胸腺裸鼠造血的特征]
Biull Eksp Biol Med. 1977 Apr;83(4):463-4.
2
Hematopoiesis of hereditarily asplenic-athymic (lasat) mice.遗传性无脾无胸腺(lasat)小鼠的造血作用
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3
Hematopoiesis in hereditarily athymic mice.遗传性无胸腺小鼠的造血作用
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4
[Recovery of hematopoiesis in mice following a continuous irradiation with a dose rate of 0.957 Gy/d and a total accumulated dose of 19.14 Gy. I. Bone marrow, spleen and thymus gland].[以0.957 Gy/d的剂量率连续照射且总累积剂量为19.14 Gy后小鼠造血功能的恢复。I. 骨髓、脾脏和胸腺]
Folia Haematol Int Mag Klin Morphol Blutforsch. 1983;110(4):564-71.
5
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6
[Hematopoietic functions in hypokinesia].
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7
The role of spleen in development of lympho-Hemopoietic tissues: effect of splenectomy on development of blood cells, bone marrow, thymus and lymph node.脾脏在淋巴造血组织发育中的作用:脾切除对血细胞、骨髓、胸腺和淋巴结发育的影响。
Anat Rec. 1968 Apr;160(4):781-93. doi: 10.1002/ar.1091600413.
8
T-cell development in the absence of a thymus: the number, the phenotype, and the functional capacity of T lymphocytes in nude mice.无胸腺情况下的T细胞发育:裸鼠中T淋巴细胞的数量、表型及功能能力
Am J Anat. 1984 Jul;170(3):339-47. doi: 10.1002/aja.1001700309.
9
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Vestn Akad Med Nauk SSSR. 1975(8):81-9.
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[Role of the hypophysis-adrenal cortex system in the pathogenesis of states of stress (on the problem of changes in organs of hematopoiesis)].垂体-肾上腺皮质系统在应激状态发病机制中的作用(关于造血器官变化问题)
Vestn Akad Med Nauk SSSR. 1969;24(7):23-34.