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[无胸腺裸鼠造血的特征]

[Characteristics of hematopoiesis in athymic nude mice].

作者信息

Gol'dberg E D, Karpova G V, Novitskiĭ V V, Iunker V M, Morozkova T S

出版信息

Biull Eksp Biol Med. 1977 Apr;83(4):463-4.

PMID:870112
Abstract

The bone marrow, peripheral blood and spleen state was studied from the age aspect in Nude mice characterized by recessive nu mutation. A number of blood system peculiarities were revealed in homozygotic (nu/nu) mice by which they differed from the heterozygotic (nu/+) animals: low peripheral blood, bone marrow and spleen lymphocyte count, erythropoiesis depression in the bone marrow and erythroid element hyperplasia in the spleen.

摘要

从年龄方面研究了具有隐性裸突变特征的裸鼠的骨髓、外周血和脾脏状态。在纯合子(nu/nu)小鼠中发现了许多血液系统特性,这些特性使它们与杂合子(nu/+)动物不同:外周血、骨髓和脾脏淋巴细胞计数低,骨髓红细胞生成受抑制,脾脏红系成分增生。

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