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儿童输尿管反流的管理

The management of ureteric reflux in children.

作者信息

Scott J E

出版信息

Br J Urol. 1977 Apr;49(2):109-18. doi: 10.1111/j.1464-410x.1977.tb04081.x.

Abstract

A series of 262 children suffering from vesico-ureteric reflux is presented. Nearly all presented with a urinary tract infection and the age at onset of symptoms was predominantly in the pre-school years. The reflux was not diagnosed in the majority until after the children started attending school. Over one-third had symptoms for more than half their lives before reflux was diagnosed. The incidence of hypertension and renal insufficiency in the series were 4% and 7-8% respectively. Nearly 60% of the children were selected by defined criteria for operation as their initial treatment. The remainder were treated conservatively in the first instance but 30% of these subsequently required operation. Reflux was eliminated in 96.3% of the children at the first operation and 5.5% developed postoperative ureteric dilatation, none of them permanently. Reflux disappeared spontaneously in two-thirds of the children treated conservatively but took more than 3 years in 46%. Infection recurred in 24% of children treated by operation and in 29% treated conservatively. The incidence with which reflux disappeared spontaneously in the children treated conservatively was related to time, not to the infection recurrence rate.

摘要

本文介绍了262例患有膀胱输尿管反流的儿童。几乎所有患儿都因尿路感染就诊,症状出现的年龄主要在学龄前。大多数患儿直到开始上学后才被诊断出反流。超过三分之一的患儿在反流被诊断之前,症状已持续超过半生时间。该系列中高血压和肾功能不全的发生率分别为4%和7 - 8%。近60%的患儿根据明确标准被选定接受手术作为初始治疗。其余患儿首先接受保守治疗,但其中30%随后需要手术。首次手术时,96.3%的患儿反流得以消除,5.5%出现术后输尿管扩张,但均非永久性。在接受保守治疗的患儿中,三分之二的反流自然消失,但46%的患儿需要超过3年时间。手术治疗的患儿中有24%感染复发,保守治疗的患儿中有29%感染复发。保守治疗患儿中反流自然消失的发生率与时间有关,而非与感染复发率有关。

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