Clark C P, Solomon H, Lambert M A, Cartmell L W, Fulmer J M, O'Leary J P
Department of Surgery, Baylor University Medical Center, Dallas, Tex, USA.
South Med J. 1996 Aug;89(8):786-92. doi: 10.1097/00007611-199608000-00006.
To assess the effects of high doses of shock waves to organs in the right upper quadrant of the abdomen, 36 adolescent swine were given one treatment of either 2,000 (2k), 6,000 (6k), or 10,000 (10k) shock waves at 24 kV peak pressure using a spark-gap lithotriptor. Shock waves were sonographically focused on the lumen of the gallbladder. Blood and tissue were examined for each group at 48 hours, at 35 days, and at 6 months. This study showed that administration of up to five times the accepted upper limit of shock waves produced no permanent damage. Transient injury, most commonly hematoma, was encountered. No posttreatment intra-abdominal catastrophes occurred. Although no renal injury was seen, it should be noted that the focus of maximum energy was 5 cm cephalad to the right kidney. This study suggests that an increased number of shock waves may be administered safely to this area of the abdomen.
为评估高剂量冲击波对右上腹器官的影响，使用火花隙碎石机，以24 kV峰值压力对36只青春期猪进行单次治疗，分别施加2000（2k）、6000（6k）或10000（10k）次冲击波。冲击波通过超声聚焦于胆囊腔。在48小时、35天和6个月时对每组的血液和组织进行检查。该研究表明，给予高达公认冲击波上限五倍的剂量未产生永久性损伤。出现了短暂性损伤，最常见的是血肿。未发生治疗后腹腔内灾难性事件。虽然未观察到肾损伤，但应注意最大能量聚焦点在右肾上方5 cm处。本研究表明，可安全地对腹部该区域施加更多次数的冲击波。
