Wronkowski Z, Stemmermann G, Rellahan W
Cancer. 1977 May;39(5):2310-6. doi: 10.1002/1097-0142(197705)39:5<2310::aid-cncr2820390553>3.0.co;2-l.
A review of Caucasian and Hawaiian patients with stomach carcinoma in Honolulu reinforces observations in other racial groups that the Lauren diffuse histopathological type of gastric cancer is more frequent in females and younger patients, while the so-called intestinal type is more common in older patients and men; that the intestinal form has a better prognosis; and that there are more long-term survivors among women than men with diffuse carcinoma. Prognosis and the level of cancer risk are not associated in Hawaii, since Hawaiians share high risk with Japanese and poor prognosis with Caucasians. There is no apparent association of cancer risk with the ratio of intestinal to diffuse forms among Hawaiians, Caucasians, and Japanese. In addition to the known high risk of stomach carcinoma in Hawaiians and Japanese, this study has identified a high risk among people of Portuguese ancestry.
对檀香山白种人和夏威夷胃癌患者的一项回顾研究,进一步证实了在其他种族群体中的观察结果:劳伦弥漫型组织病理学类型的胃癌在女性和年轻患者中更为常见,而所谓的肠型在老年患者和男性中更为普遍;肠型预后较好;弥漫型癌的女性长期存活者多于男性。在夏威夷,预后与癌症风险水平无关,因为夏威夷人与日本人患癌风险高,而与白种人预后差。在夏威夷人、白种人和日本人中,癌症风险与肠型和弥漫型的比例没有明显关联。除了已知夏威夷人和日本人患胃癌风险高之外,本研究还发现葡萄牙裔人群患癌风险也高。