犬心脏的反应性充血：腺苷、三磷酸腺苷和氨茶碱之间的相互关系以及吲哚美辛的作用
Reactive hyperaemia in the dog heart: inter-relations between adenosine, ATP, and aminophylline and the effect of indomethacin.
作者信息
Giles R W, Wilcken D E
出版信息
Cardiovasc Res. 1977 Mar;11(2):113-21. doi: 10.1093/cvr/11.2.113.
PMID:870195
Abstract
Intracoronary adenosine, ATP, and the release of an 8 second occlusion increased coronary blood flow (CBF) to a similar extent. Aminophylline decreased the CBF response to adenosine by 80% and that to an 8 s occlusion by 20% but did not change the CBF response to ATP. Indomethacin had no effect on CBF. The results suggest that the increase in CBF after brief occlusions is not mediated in a major way by adenosine or prostaglandins.
摘要
冠状动脉内注入腺苷、三磷酸腺苷（ATP）以及8秒的血管闭塞，均可使冠状动脉血流量（CBF）增加至相似程度。氨茶碱使CBF对腺苷的反应降低80%，使CBF对8秒血管闭塞的反应降低20%，但未改变CBF对ATP的反应。吲哚美辛对CBF无影响。结果表明，短暂血管闭塞后CBF的增加并非主要由腺苷或前列腺素介导。
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